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Availability: IN STOCK - 1 AVAILABLE
Sku: BLE1800300
Category: Bioreactors
Manufacturer: Thales Nanotechnology
The H-Cube Pro™ is the next generation version of the number one selling flow reactor, the H-Cube®. The H-Cube Pro™ takes the best of the H-Cube®, such as fast reactions, safe high pressure hydrogen generation from water, catalyst cartridges, and ease of use, and improves upon it dramatically.
  • Flow rate range: 0.3 - 3 mL/min
  • Temperature range: 10 - 150 °C
  • Pressure range: Atmospheric to 100 bar
  • Hydrogenation Production range 0 – 60 cm3 /min
  • Water reservoir capacity 340 mL
  • Dimensions of H-Cube Pro™ including touch screen:
  • Height: 400 mm (15.75”)
  • Width: 470 mm (14.6”)
  • Length: 510 mm (20.1”)
  • Weight of H-Cube Pro™: 23 kg (46.3 lbs)
  • Voltage: 85 - 264 VAC Frequency: 47 - 63Hz
  • Dimensions of HPLC pump:
  • ​Height: 130 mm (5.1”)
  • Width: 110 mm (4.3”)
  • Length: 220 mm (8.7”)
  • Weight of HPLC pump: 2.32 kg (5.1 lbs)


Parameter  H-Cube®  H-Cube Pro™  Used for
Hardware related
Maximum temperature 100 °C 150 °C Performing more difficult or different chemistry, such as oxidation with O2 from the Gas Module.
Minimum Temperature    RT  10 °C  Selective/exothermic reactions
Capacity of hydrogen production  30 mL/min 60 mL/min Higher throughput
Inlet and Outlet Valve Switch  Waste With upgrade  Built in Easier semi-automated change between Solvent and Reagent, and and Product on the Software. No more manually transferring the line between flasks.
Software related
Timer With upgrade Built in Automatic reaction running.
Data logging and exporting Not available

What can be set:

▪ CatCart type

 ▪ Solvent    

▪ Reagent

 What is monitored over time:

▪ Bubble detector

 ▪ Temperature at different places

▪ Pressure (inlet, system, H2)

Data can be exported so the system acts as a lab book as well
Reaction Parameter Not available Can save reaction parameters of desired  reactions or upload ThalesNano’s  recommended starting conditions for various reactions. Ease of use, time saving.
Calculation  Not available Built in Simplex Algorithm.   For faster optimization, the system recommends reaction conditions to obtain the best conversion, yield, or selectivity.
Priming   Not available Part of Starting Process System will start system at high flow rate to eliminate air from the reaction line.
Hydrogen Production Change Just 0, 7%, or 100% The modes functions have been removed for simplicity. You can now  vary the amount of hydrogen production from 0 to 100% in increments of 1.  To obtain greater selectivity.
Manual Pressure Start   In No H2 mode possible   Quickly varying the pressure.    For diagnostic purposes and to bed in the teflon membrane.
External Module control  Not available  Built in     Full control over ThalesNano’s modules with a number of extra safety features implemented.

 External PC software can control: Autosampler, 

CatCart Changer and H-Cube

External PC software can control: Autosampler, CatCart Changer,  H-Cube Pro, Gas Module and Phoenix Flow Reactor Allows automated catalyst screening and/or reaction optimization of even triphasic reactions other than hydrogenation


Click here to see the manual